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DeCS
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Descriptor English:
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Myasthenia Gravis, Neonatal
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Descriptor Spanish:
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Miastenia Gravis Neonatal
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Descriptor Portuguese:
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Miastenia Gravis Neonatal
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Synonyms English:
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Antenatal Myasthenia Gravis
Neonatal Myasthenia Gravis
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Tree Number:
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C10.114.656.650
C10.668.758.725.650
C20.111.258.500.650
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Definition English:
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A disorder of neuromuscular transmission that occurs in a minority of newborns born to women with myasthenia gravis. Clinical features are usually present at birth or develop in the first 3 days of life and consist of hypotonia and impaired respiratory, suck, and swallowing abilities. This condition is associated with the passive transfer of acetylcholine receptor antibodies through the placenta. In the majority of infants the myasthenic weakness resolves (i.e., transient neonatal myasthenia gravis) although this disorder may rarely continue beyond the neonatal period (i.e., persistent neonatal myasthenia gravis). (From Menkes, Textbook of Child Neurology, 5th ed, p823; Neurology 1997 Jan;48(1):50-4) |
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History Note English:
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2000
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Allowable Qualifiers English:
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Record Number:
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34210
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Unique Identifier:
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D020941
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Occurrence in VHL:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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